If you decide to hide from the mark of the beast in a desert, the terrain is difficult because of extreme fluctuations between heat and cold, plus lack of water and often food. Also if drones are used to hunt for you there most of the time there is a lack of cover.
There are a few big advantages though. Solar power is one of the biggest advantages. The bright intense sun will help you to get a lot of solar power stored up daily if you have the right equipment. This can charge lighters to get fire, USB power-bank powered heating pads for the cold nights, laptops, phones and tablets (if you can block tracking of them) and many other things ca be charged.